Helminth-Microbe Co-Infection: Insights from a Natural System

Abstract

Concurrent infection by multiple parasites can shape the trajectory and outcome of infectious diseases. For example, coinfections with parasitic worms can affect the progression and severity of microbial infections, including many viral and bacterial infections. Although an increasing number of studies are investigating the consequences of worm-microbe coinfections in laboratory settings, we still know very little about the repercussions of coinfection in natural environments. This is despite the fact that a majority of hosts (including humans) are infected with multiple parasites simultaneously. To understand the impacts of worm coinfection in natural populations, my laboratory studies interactions between gastrointestinal worm infections and bovine tuberculosis in free-ranging African buffalo. Using a coupled experimental and longitudinal study design, our work is revealing that both active infection with worms, and the host's constitutive response to worm infection, have profound implications for the outcome of tuberculosis at the individual and population levels.

Presenters

Image
A headshot of Vanessa Ezenwa

Vanessa Ezenwa

Dr. Vanessa Ezenwa is a Professor at the University of Georgia, where she holds joint appointments in the Odum School of Ecology and College of Veterinary Medicine. She received a BA in Biology from Rice University, and PhD in Ecology and Evolutionary Biology from Princeton University. Her research centers on the ecology of infectious diseases in wild animal populations, with a specific focus on linking processes across scales of biological organization. Work in Dr. Ezenwa’s lab combines field studies with molecular and theoretical approaches to address key questions about the dynamics of...

Image
A headshot of Vanessa Ezenwa

Vanessa Ezenwa

Dr. Vanessa Ezenwa is a Professor at the University of Georgia, where she holds joint appointments in the Odum School of Ecology and College of Veterinary Medicine. She received a BA in Biology from Rice University, and PhD in Ecology and Evolutionary Biology from Princeton University. Her research centers on the ecology of infectious diseases in wild animal populations, with a specific focus on linking processes across scales of biological organization. Work in Dr. Ezenwa’s lab combines field studies with molecular and theoretical approaches to address key questions about the dynamics of parasitism in natural systems.

Presenters
Vanessa Ezenwa, University of Georgia
Date
Time
11:00 a.m. ET
Location
SESYNC – 1 Park Place, Suite 300 Annapolis, MD 21401
Share